跳至主要内容

Mechanism and functional efficacy of hydroxyapatite nanopowder

As a drug carrier:
Hydroxyapatite nanopowder have many advantages such as good biocompatibility, low pH sensitivity, controllable structure, large drug loading and high encapsulation efficiency, and are widely used as drug carriers. At the same time, the synthetic hydroxyapatite is surface-modified to load a specific drug, and can also solve the problem of release of drug release.
Hydroxyapatite nanopowder
Hydroxyapatite is the main component of human teeth and osteophytes:

The hydroxyapatite nanopowderl is similar to the human bone structure and has similar biocompatibility, and is widely used in bone defect repair. Nano-sized fibrous hydroxyapatite or porous network hydroxyapatite prepared by controlled conditions, the surface of the material is favorable for the attachment of osteoblasts, and the pore structure is beneficial to the growth and differentiation of osteoblasts, and can promote bone repair and growth. At the same time, in combination with other antibacterial means, it will be a dual-effect material with bone growth and anti-infection, which is a research hotspot.
Hydroxyapatite nanopowder
As an anti-tumor "new weapon":

Studies have shown that nano-hydroxyapatite exhibits excellent anti-tumor activity, and its anti-tumor mechanism is a mitochondria-dependent apoptotic pathway and a negative regulation of the PIK3/AKT pathway for the development of advanced biocompatible nanocrystals for nanomedicine. Has a high value.
Hydroxyapatite nanopowder
Nano-hydroxyapatite performance advantage

1. Good biocompatibility and stability, large specific surface area, biodegradable, inherent antibacterial activity,
Rich in modification sites
2. Low cost and simple preparation process
Application prospects
Simple hydroxyapatite materials have not been able to meet today's needs, more are seeking
The combination of hydroxyapatite and other materials, which plays a role in the excellent properties of hydroxyapatite
Based on the development of multi-functional composite materials:
Hydroxyapatite is combined with Au and Ag to obtain a composite material having an antibacterial effect;
Hydroxyapatite combined with carbon dots,
Anti-tumor composite materials utilizing carbon dot radiation properties;
Magnetic iron oxide combined with hydroxyapatite,
A targeted anti-tumor drug carrier or the like is obtained.
Hydroxyapatite nanopowder

评论

此博客中的热门博文

Acetamiprid is one of the safety Insecticide for agriculture

Insecticide acetamiprid  is an organic compound with the chemical formula C10H11ClN4. It is an odorless neonicotinoid insecticide produced under the trade names Assail, and Chipco by Aventis CropSciences. It is systemic and intended to control sucking insects (Lepidoptera, Thysanoptera, Hemiptera, mainly aphids) on crops such as leafy vegetables, citrus fruits, pome fruits, grapes, cotton, cole crops, and ornamental plants. It is also a key pesticide in commercial cherry farming due to its effectiveness against the larvae of the cherry fruit fly. Insecticide acetamiprid  is an insecticide belonging to the chloropyridinyl neonicotinoids, this family of insecticides was introduced in the early 1990s. This compound is an insecticide that is introduced for controlling pests, but also for domestic use to control fleas on cats and dogs. Mechanism of action: Insecticide acetamiprid  is a nicotine-like substance and reacts to the body in a similar way as nicotine. Nicotine is a n...

Sodium Cyclamate

Sodium cyclamate is no harm to human and has sugar-free and low-calorie food-grade sweetener although 30-50 times sweeter than sucrose .Sodium cyclamate is physically stable, resistent to heart acid and alkaline. Food additives sweeteners Sodium Cyclamate wholesale Sodium cyclamate is a white needle, flake or crystalline powder, an active pharmaceutical ingredient product that is stable under heat, does not absorb moisture in the air, does not ferment, and food grade cyclamate should be stored in a cool, dry, well ventilated place. He is a non-nutritive synthetic sweetener with a sweetness of 30-50 times that of sucrose and a price of only one-third of sucrose. It is widely used as a food additive in the world for refreshing beverages, fruit juices, ice cream, pastry foods and preserves. - Taste sweet,no bitter feeling - Harmless to health - Physically stable,resistent to heat,acid and alkaline - Easy of storage,do not absorb water from air,does not ferment Application: Sodium cyclama...

Hydroxyapatite - the new century bone

Due to the influence of diseases, aging, frequent traffic accidents and other factors, the number of cases of bone injury has increased year by year. According to statistics, there are 3 million orthopedic cases every year in China, and the demand for bone substitute materials is increasing. In recent years, bone substitute materials represented by hydroxyapatite have gradually become the darling of clinical application. Hydroxyapatite  is a major component of vertebrate bones and teeth and has good biological activity and biocompatibility. Compared with traditional metal (stainless steel, titanium alloy) and ceramic (alumina, silicon nitride) bone substitute materials, hydroxyapatite is not only highly resistant to corrosion and osteoinductive, but also its degradation in vivo is eliminated. The security risks of the former. At present, the research on hydroxyapatite in bone substitute materials mainly focuses on two aspects, hydroxyapatite coating and human bone bionic regenerati...