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  We have developed a practical procedure for expedient and cost-effective synthesis of small to medium-sized membrane proteins in multi-milligram scale through the use of automated Fmoc chemistry. After the attachment of a removable arginine-tagged backbone modification group, the membrane protein segments behave almost the same as ordinary water-soluble peptides in terms of Fmoc solid-phase synthesis, ligation, purification, and mass spectrometry characterization. The efficiency and practicality of the method is demonstrated by the successful preparation of Ser64-phosphorylated M2 proton channel from influenza A virus and the membrane-embedded domain of an inward rectifier K+ channel protein Kir5.1.  Figure1. Removable Arg-tagged backbone modification for chemical synthesis of membrane proteins Reference: ------------------------------------------------------------------------------------ 1.Zheng, J. S. et al. Expedient total synthesis of small to medium-sized membrane prot...

  Quality of fresh meat is closely linked with human’s health. Bacterial contamination and freshness of meat are the key factors to show such quality. But TVB_N detection takes long time about 48 hours to get results, and sensory evaluation is not reliable sometimes. A rapid and accurate method to detect is necessary. TAL reagent  could be applied to detect bacterial contamination and freshness of meat. Because the main bacterial contamination of meat is gram-negative bacteria, which releases endotoxins when it dies. And endotoxins could be detected or quantified by TAL reagent. We will briefly describe how to check bacterial contamination and freshness of meat through TAL reagent here. Materials and Methods 1.BIOENDO TAL reagent. Test for confirmation of labeled lysate sensitivity should be carried out when a new batch of lysate is used or when there is any change in the test conditions that may affect the outcome of the test. 2. BIOENDO Water for BET  and diluent. Water...

In 2018,  SAT NANO  launched a special spherical powder for refractory metal  3D printing . Recently, SATNANO used its independent research and development intellectual property rights to provide customers with customized spherical tungsten powder, and tried to print tungsten series shielding parts. The whole series of parts adopt a thin-wall structure and the minimum wall thickness is only 0.1mm. As we all know, tungsten shields have good radiation shielding performance and use performance, and are widely used in PET rooms, linear accelerators, HDR rooms, gamma knives and nuclear power plants. Compared with traditional shielding materials, tungsten has higher density and better ray absorption ability, which can greatly reduce the volume of the shielding without weakening its shielding performance; in addition, tungsten shields are non-toxic and will not cause harm to the human body Hazard; and the purity of the formed parts reaches 99.9%, and the thermal conductivity abo...

Niobium (Nb) is a refractory metal with a high melting point (2468°C), moderate density, corrosion resistance, radiation resistance, high temperature strength, and good high temperature mechanical properties. The excellent properties of niobium and niobium alloys make it one of the important candidate materials for high-temperature structural parts in the aviation, aerospace and nuclear industries, and can be used to manufacture key components such as rocket engines and nuclear reactors. However, its oxidation performance is poor. Pure niobium undergoes "pest" oxidation at 600°C. As the temperature increases, the degree of oxidation intensifies, eventually leading to the failure of its high-temperature performance. This shortcoming severely restricts niobium and niobium. Application of alloys. In order to improve its high temperature oxidation resistance, surface coating protection is a practical and effective way to balance the high temperature mechanical properties and oxi...

Application of alumina powder: As a polishing powder, this is an important application of nano alumina powder. It involves stainless steel mirror polishing, titanium metal polishing, cast iron polishing, aluminum mirror polishing, stone polishing, paint polishing, resin polishing, PCB polishing, glass polishing, optical glass, spectacle lens polishing, resin lens polishing, sapphire polishing, LED polishing, germanium Polishing, zinc polishing, etc. Specification of alumina powder: CAS No:1344-28-1 ENINEC No.:215-691-6 SAT NANO supply the nano aluminum oxide, alumina, al2o3 powder, 100nm, 200nm particle, 99.99% purity, white powder form. It is widely used as polishing powder. SAT NANO as one of the best supplier of Al2o3 aluminum oxide powder, we not only supply the powder but also supply the solution, please feel free to contact us at admin@satnano.com

What is a thermally conductive gel? Thermally conductive gel: It has some advantages of thermally conductive silicone sheet and thermally conductive silicone grease, while making up for some of the weaknesses of the two; strong plasticity, can fill uneven interfaces. What are the advantages of thermal gel? 1. Efficient thermal conductivity; 2. Low compressive force application and low stress; 3. High compression ratio; 4. High electrical insulation; 5. Good temperature resistance; 6. It can realize automatic use and other performance. Thermal gel application range: 1. Graphics card, video memory, computer equipment 2. Host or office network equipment 3. New energy equipment such as solar panels 4. Mini heat pipe radiator 5. Automobile engine control device 6. Communication hardware 7. Portable electronic devices 8. Semiconductor automatic test equipment 9. LCD display device For this reason, SAT NANO specially designed thermal conductive  alumina  ther...

Nanotechnology has been successfully applied in China's medical field. A group in Nanjing used  nano silver  technology to develop and produce a medical dressing, a long-acting broad-spectrum antibacterial cotton. The production principle of this antibacterial cotton is to make silver into 20 nanometer ultrafine particles through nanotechnology, and then attach it to cotton fabric. Silver has the effect of preventing ulcers and accelerating wound healing. After the nanotechnology treatment, the surface of silver increases sharply, the surface structure changes, and the sterilization ability increases by about 200 times. It has a good inhibitory effect on clinical common surgical infections. Nanoparticles and nanoparticles are used as drug delivery systems. The basic properties of the materials they produce are non-toxic, stable, good biological properties, and do not chemically react with drugs. Nanosystems are mainly used for the administration of drugs with high toxicity, sh...